The study done by a team of researchers at the Johns Hopkins Bloomberg School of Public Health have claimed that gender differences can be important in predicating the response of vaccines.

It was corroborated by a data which was released from adult and child vaccine trials that believes that gender is important but the predictor of vaccine response that could help predict the efficacy of combating infectious disease.

According to Sabra Klein, PhD, lead author of the review and an assistant professor at the Bloomberg School's W. Harry Feinstone Department of Molecular Microbiology and Immunology, "Sex can affect the frequency and severity of adverse effects of vaccination, including fever, pain and inflammation."

In addition to this pregnancy can also alter in bringing significant changes in individuals.

This piece of article was published in the May issue of The Lancet Infectious Diseases.